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Innovative Journal of Medical Imaging

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eISSN: 3048-5568

Review Article

Comparative Evaluation of Multipara-metric Magnetic Resonance Imaging and Micro-Ultrasound for the Detection of Clinically Significant Prostate Cancer

Innovative Journal of Medical Imaging | Volume 3, Issue 1 | March 2026
Authors: Mani Pratap Singh, Vanshu Saxena
Received: Feb 04, 2026 Accepted: Mar 15, 2026 Published: Mar 28, 2026
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Abstract

Prostate cancer remains one of the most prevalent malignancies among men worldwide, necessitating accurate and early detection of clinically significant disease to guide appropriate management. In recent years, imaging modalities such as multiparametric magnetic resonance imaging (mpMRI) and micro-ultrasound (micro-US) have emerged as valuable tools in the diagnostic pathway. This review provides a comprehensive analysis and comparison of mpMRI and micro-US in identifying clinically significant prostate cancer. mpMRI, incorporating T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced sequences, has demonstrated high sensitivity and standardized reporting through PI-RADS, improving lesion localization and risk stratification. Conversely, micro-ultrasound offers real-time, high-resolution imaging with enhanced spatial detail, enabling targeted biopsy using the PRI-MUS protocol without the need for contrast agents. The review critically evaluates diagnostic accuracy, sensitivity, specificity, cost-effectiveness, accessibility, and operator dependency of both modalities. Additionally, emerging evidence on combined and complementary use is discussed. While mpMRI remains the current reference standard, micro-ultrasound shows promising potential as a cost-effective and accessible alternative. Further large-scale, multicenter studies are required to establish standardized protocols and validate long-term clinical outcomes.

Keywords: Multiparametric MRI, Micro-ultrasound, Prostate cancer, Diagnostic

Article Information
DOI: 10.62502/ijmi/v3i1art1
Journal: Innovative Journal of Medical Imaging
Abbreviation: Innov. J. Med. Imaging
ISSN (Online): 3048-5568
Volume/Issue: 3(1)
Pages: 1-6
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How to Cite
Vancouver Style:
Singh MP, Saxena V. Comparative Evaluation of Multipara-metric Magnetic Resonance Imaging and Micro-Ultrasound for the Detection of Clinically Significant Prostate Cancer. Innov. J. Med. Imaging 2026;3(1):1-6. doi: 10.62502/ijmi/v3i1art1
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Article Details

Article Type:
Review Article

Volume/Issue:
3(1)

Year:
2026

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